What makes a she a he?

I say you can certainly be whoever you want to be, and if you just feel that people should call you "Mister" and refer to you as "he" or "him", despite the fact that you have breasts and a vagina, well, go ahead. I don't think it really matters. But I still don't get it.

Even if you don't know James is still a biological female, at first glance the two seem an unlikely couple. Burden is tall, thin and angular, with fair skin, glasses and strawberry blond hair cropped to frame her face. Standing next to her and barely reaching her shoulder, James could be her younger brother. He stands just 5 feet tall, wears a baseball cap over his short brown hair and dresses in polo shirts and cargo shorts. His age is more evident when he speaks, his brown, wide-set eyes and easy banter showing a rare, hard-won confidence.

This girl thinks she's a guy. She doesn't just wish she was a guy. She believes she is! Even though she's got a woman's body. I just wonder, how can you feel like you're a man if you've never been one? Oh well.